Dextromethorphan (DXM) is a cough suppressant found in more than 120 over-the-counter (OTC) cold medications, either alone or in combination with other drugs such as analgesics (e.g., acetaminophen), antihistamines (e.g., chlorpheniramine), decongestants (e.g., pseudoephedrine), and/ or expectorants (e.g., guaifenesin).

Xylazine, reported as an adulterant in an increasing number of illicit drug mixtures, has also been detected in a growing number of overdose deaths. It is commonly encountered in combination with fentanyl but has also been detected in mixtures containing cocaine, heroin, and a variety of other drugs. However, xylazine...

The U.S. Drug Enforcement Administration has released the 2022 edition of Drugs of Abuse, A DEA Resource Guide, which is designed to be a reliable resource on the most commonly used and misused drugs in the United States. Released on a periodic basis, Drugs of Abuse provides important science-based information...

“Fentanyl is the single deadliest drug threat our nation has ever encountered,” said Administrator Anne Milgram. “Fentanyl is everywhere. From large metropolitan areas to rural America, no community is safe from this poison. We must take every opportunity to spread the word to prevent fentanyl-related overdose death and poisonings from...

This case should send a clear message to any foreign leader who corruptly abuses their power to support drug cartels. If you take drug money for your election, if you accept drug cartel bribes, if you traffic deadly drugs, if you protect criminal drug cartels, if you turn the power...

DEA Administrator Anne Milgram's remarks (as delivered) at a December 16, 2021 press conference announcing the results of "One Pill Can Kill" Phase Two

DEA officials report a dramatic rise in the number of fake pills containing at least 2 mg of fentanyl, which is considered a deadly dose.

What is it? Many counterfeit pills are made to look like prescription opioids – such as oxycodone (Oxycontin®, Percocet®), hydrocodone (Vicodin®), and alprazolam (Xanax®); or stimulants like amphetamines (Adderall®) – but contain fentanyl or methamphetamine. Criminal drug networks are mass-producing fake pills and falsely marketing them as legitimate prescription pills...

Many counterfeit pills are made to look like prescription opioids – such as oxycodone (Oxycontin®, Percocet®), hydrocodone (Vicodin®), and alprazolam (Xanax®); or stimulants like amphetamines (Adderall®) – but contain fentanyl or methamphetamine. Criminal drug networks are mass-producing fake pills and falsely marketing them as legitimate prescription pills to deceive the...

The 2018 National Drug Threat Assessment (NDTA) is a comprehensive strategic assessment of the threat posed to the United States by domestic and international drug trafficking and the abuse of illicit drugs. The report combines federal, state, local, and tribal law enforcement reporting; public health data; open source reporting; and...