Education plays a critical role in preventing substance use and misuse. Drugs of Abuse, A DEA Resource Guide, is designed to be a reliable resource on the most commonly used and misused drugs in the United States. This comprehensive guide provides important information about the harms and consequences of drug...

DEA has prepared this product primarily for law enforcement counterparts (state, local and tribal) and public safety and protection officials with a focus on enduring and emerging threats at both the national and regional levels. This report represents what will be the first of regular STREET reports prepared for and...

WASHINGTON – DEA first warned the public of a sharp increase in fentanyl seizures containing xylazine in our March 2023 Public Safety Alert . Since that time, xylazine’s growing prevalence in the fentanyl supply continues to make the deadliest drug threat facing this country even deadlier. In 2023, 30% of...

DEA has prepared this product primarily for law enforcement counterparts (state, local and tribal) and public safety and protection officials with a focus on enduring and emerging threats at both the national and regional levels. This report represents what will be the first of regular STREET reports prepared for and...

INTREPID confirms both liquid veterinary preparations and powdered xylazine are being used to adulterate fentanyl. INTREPID observed chemical markers in xylazine seizures that can assist in determining precursors, synthetic routes, and potentially connecting cases.

“In this moment, when the United States is suffering tens of thousands of opioid-related drug poisoning deaths every year, the DEA’s top priority is doing everything in our power to save lives,” said Administrator Milgram. “Medication for opioid use disorder helps those who are fighting to overcome substance use disorder...

Xylazine, reported as an adulterant in an increasing number of illicit drug mixtures, has also been detected in a growing number of overdose deaths. It is commonly encountered in combination with fentanyl but has also been detected in mixtures containing cocaine, heroin, and a variety of other drugs. However, xylazine...

“Fentanyl is the single deadliest drug threat our nation has ever encountered,” said Administrator Anne Milgram. “Fentanyl is everywhere. From large metropolitan areas to rural America, no community is safe from this poison. We must take every opportunity to spread the word to prevent fentanyl-related overdose death and poisonings from...

The DEA’s Fentanyl Profiling Program (FPP) performs in-depth chemical analyses on fentanyl and fentanyl-related samples obtained from seizures throughout the United States. This report summarizes the findings for these analyses for Calendar Year 2021. FPP data is not intended to reflect U.S. market share, but is rather a snapshot of...

DEA Administrator Anne Milgram's statement on a potential mass fentanyl poisoning event in Gadsden County, Florida on July 2, 2022.